Alnylam Pharmaceuticals, Inc.

NasdaqGS-ALNY

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Assets	LTM	Dec '24	Dec '23	Dec '22	Dec '21	Dec '20	Dec '19	Dec '18	Dec '17	Dec '16	Dec '15
Cash and Cash Equivalents	1,490.2	966.4	812.7	866.4	820	496.6	547.2	420.1	645.4	193.6	180.9
Cash and Cash Equivalents
Short-Term Investments	1,234.4	1,728.1	1,626.7	1,326	1,615.6	1,377.8	989	664	1,045.3	433.2	899.6
Marketable Securities
Investment in Equity Securities of Regulus Therapeutics Inc
Marketable Debt Securities
Marketable Equity Securities
Total Cash and Cash Equivalents	2,724.6	2,694.5	2,439.4	2,192.4	2,435.6	1,874.4	1,536.2	1,084.2	1,690.6	626.8	1,080.5
Accounts Receivable	964.8	405.3	327.8	238	198.6	102.4	43	18.8	34	—	—
Accounts Receivable, Net
Other Receivables	—	—	—	—	—	500	—	—	—	23.3	8.3
Billed and Unbilled Collaboration Receivables
Related Party Notes Receivable
Income Taxes Receivable
Receivable Related to the Sale of Future Royalties
Total Trade Receivables	964.8	405.3	327.8	238	198.6	602.4	43	18.8	34	23.3	8.3
Inventories	75.4	78.5	89.1	129	86.4	75.2	56.3	24.1	—	—	—
Inventory
Other Current Assets	188	117	126.4	132.9	88.1	62.8	80.3	73.7	40.1	21.7	16.6
Prepaid Expenses and Other Current Assets
Deferred Tax Assets
Total Current Assets	3,952.8	3,295.3	2,982.7	2,692.2	2,808.6	2,614.8	1,715.9	1,200.7	1,764.7	671.9	1,105.4
Total Current Assets
Net Property, Plant & Equipment	693.1	693.9	725.8	738.6	733.6	706.5	646.4	320.7	181.9	114.6	27.8
Property, Plant and Equipment, Net
Operating Lease Right-of-Use Assets
Net Intangible Assets	—	—	—	—	—	—	—	—	—	—	—
Intangible Assets, Net
Long-Term Investments	51.3	68.6	49.4	49.4	40.9	40.7	14.8	44.8	43.9	474.8	251.8
Marketable Securities
Marketable Debt Securities
Investment in Equity Securities of Regulus Therapeutics Inc
Restricted Investments
Other Long-Term Assets	154.4	182.2	72	66.1	60.2	45	18.1	8.6	4.2	1.6	1.5
Restricted Cash, Net of Current Portion
Deferred Tax Assets, Net of Current Portion
Deferred Tax Assets
Restricted Cash
Other Assets
Total Assets	4,851.7	4,240	3,829.9	3,546.4	3,643.3	3,407.1	2,395.1	1,574.8	1,994.7	1,262.8	1,386.5
Total Assets

Liabilities	LTM	Dec '24	Dec '23	Dec '22	Dec '21	Dec '20	Dec '19	Dec '18	Dec '17	Dec '16	Dec '15
Accounts Payable	117.6	88.4	55.5	98.1	73.4	52	49.9	59.7	28.4	54.5	16.8
Accounts Payable
Accrued Expenses	1,153.6	793.7	713	545.5	395.2	355.9	197.2	112.7	72.2	42.1	28.8
Accrued Expenses
Current Portion of Leases	44.8	41.9	41.5	42	40.5	36.9	27.7	—	—	—	—
Operating Lease Liabilities
Unearned Revenue	2.5	55.5	102.8	42.1	149.5	127.2	77.8	3.5	41.7	33.5	15.4
Deferred Revenue
Other Current Liabilities	236.9	206.8	55	40.3	37.1	13.3	—	3.6	2	1.6	1.2
Income Taxes Payable
Deferred Tax Liabilities
Deferred Rent
Liability Related to the Sale of Future Royalties
Development Derivative Liability
Total Current Liabilities	1,555.5	1,186.3	967.8	767.9	695.7	585.3	352.6	179.5	144.3	131.7	62.1
Total Current Liabilities
Long-Term Debt	1,040.3	1,024.6	1,020.8	1,016.9	675.7	191.3	—	30	30	150	—
Long-Term Debt
Convertible Debt
Notes Payable, Net of Current Portion
Leases	223.4	229.5	243.1	261.3	281.3	293	276.1	—	—	—	—
Operating Lease Liability, Net of Current Portion
Operating Lease Liabilities, Net of Current Portion
Other Long-Term Liabilities	1,798.6	1,732.5	1,818.9	1,658.4	1,402.3	1,321.2	327.7	63.3	54	60.9	59.7
Deferred Revenue, Net of Current Portion
Deferred Rent, Net of Current Portion
Deferred Rent
Liability Related to the Sale of Future Royalties, Net of Current Portion
Development Derivative Liability, Net of Current Portion
Other Liabilities
Total Long-Term Liabilities	3,062.3	2,986.6	3,082.7	2,936.7	2,359.4	1,805.5	603.8	93.3	84	210.9	59.7
Total Liabilities	4,617.8	4,172.9	4,050.5	3,704.6	3,055.1	2,390.8	956.4	272.8	228.3	342.6	121.8
Total Liabilities

Equity	LTM	Dec '24	Dec '23	Dec '22	Dec '21	Dec '20	Dec '19	Dec '18	Dec '17	Dec '16	Dec '15
Common Stock	1.3	1.3	1.3	1.2	1.2	1.2	1.1	1	1	0.9	0.9
Common Stock
Additional Paid-in Capital	7,414.8	7,388.1	6,811.1	6,454.5	6,058.5	5,644.1	5,201.2	4,175.1	3,947.6	2,609.6	2,506.2
Additional Paid-in Capital
Accumulated Other Comprehensive Income	-21.8	-34.5	-23.4	-44.7	-33.3	-43.6	-36.5	-33.2	-34.4	-33.4	4.4
Accumulated Other Comprehensive Loss
Retained Earnings	-7,160.4	-7,287.7	-7,009.6	-6,569.3	-5,438.2	-4,585.4	-3,727.1	-2,841	-2,147.7	-1,656.8	-1,246.7
Retained Earnings
Deferred Stock-Based Compensation
Total Common Shareholders' Equity	233.9	67.1	-220.6	-158.2	588.2	1,016.2	1,438.7	1,302	1,766.4	920.2	1,264.7
Total Shareholders' Equity	233.9	67.1	-220.6	-158.2	588.2	1,016.2	1,438.7	1,302	1,766.4	920.2	1,264.7
Total Stockholders' Equity
Total Liabilities and Shareholders' Equity	4,851.7	4,240	3,829.9	3,546.4	3,643.3	3,407.1	2,395.1	1,574.8	1,994.7	1,262.8	1,386.5
Total Liabilities and Stockholders' Equity