| 43.6 | -319.1 | -269.7 | -278.2 | -332.3 | -72.9 | | | | | | | | |
| | | | | | | | | | | | | | |
Depreciation & Amortization | 56.3 | 56.5 | 57.6 | 56.7 | 56 | 55.3 | | | | | | | | |
Depreciation and Amortization | | | | | | | | | | | | | | |
Amortization and Interest Accretion Related to Operating Leases | | | | | | | | | | | | | | |
| 368.2 | 305.8 | 283.4 | 272.1 | 222.4 | 240.6 | | | | | | | | |
Stock-Based Compensation Expense | | | | | | | | | | | | | | |
| 236 | 175.5 | 206.3 | 155.2 | 195.4 | 239.2 | | | | | | | | |
Non-Cash Interest Expense on Liability Related to the Sale of Future Royalties | | | | | | | | | | | | | | |
Realized and Unrealized Loss on Marketable Equity Securities | | | | | | | | | | | | | | |
Loss on Extinguishment of Debt | | | | | | | | | | | | | | |
Change in Fair Value of Development Derivative Liability | | | | | | | | | | | | | | |
Gain on Litigation Settlement | | | | | | | | | | | | | | |
Charge for 401(k) Company Stock Match | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | |
| | | | | | | | | | | | | | |
Changes in Trade Receivables | -603.7 | -240.9 | -94.4 | -86.6 | -23.2 | -94.1 | | | | | | | | |
| | | | | | | | | | | | | | |
Billed and Unbilled Collaboration Receivables | | | | | | | | | | | | | | |
| 23.2 | 24.1 | 19.8 | 13.6 | 24.7 | 23.6 | | | | | | | | |
| | | | | | | | | | | | | | |
Changes in Accounts Payable | 187.8 | 47.9 | -59.8 | 91.1 | 114.5 | 149.7 | | | | | | | | |
Change in Accounts Payable | | | | | | | | | | | | | | |
Accounts Payable, Accrued Expenses and Other Liabilities | | | | | | | | | | | | | | |
Changes in Accrued Expenses | — | — | — | — | — | — | | | | | | | | |
Change in Accrued Expenses and Other | | | | | | | | | | | | | | |
Changes in Unearned Revenue | -65.8 | -56.3 | -234.2 | -235.4 | -204.9 | -177.4 | | | | | | | | |
| | | | | | | | | | | | | | |
Changes in Other Operating Activities | -21.5 | -9 | 45.9 | 3.2 | 1.3 | 6.3 | | | | | | | | |
Proceeds from Landlord Lease Incentive for Tenant Improvements | | | | | | | | | | | | | | |
Prepaid Expenses and Other Assets | | | | | | | | | | | | | | |
Operating Lease Liability | | | | | | | | | | | | | | |
Cash from Operating Activities | 265.9 | -15.5 | -45.1 | -8.3 | 56.6 | 372.3 | | | | | | | | |
Net Cash Provided by Operating Activities | | | | | | | | | | | | | | |