| 597.8 | 568.3 | 555.4 | 566.8 | 539.5 | 637.2 | | | | | | |
| 10.8% | -10.8% | 30.6% | 18.2% | 14.3% | 35.6% | | | | | | |
| | | | | | | | | | | | |
License, Contract and Collaboration Reimbursement Revenues | | | | | | | | | | | | |
| | | | | | | | | | | | |
Collaboration Services Revenues | | | | | | | | | | | | |
| | | | | | | | | | | | |
| 18.6 | 19.5 | 19.2 | 20 | 17.3 | 17.7 | | | | | | |
| | | | | | | | | | | | |
| 579.2 | 548.8 | 536.3 | 546.8 | 522.2 | 619.5 | | | | | | |
| 96.9% | 96.6% | 96.5% | 96.5% | 96.8% | 97.2% | | | | | | |
Selling, General & Administrative Expenses | — | 134.9 | 137.2 | 134.3 | — | 132 | | | | | | |
Selling, General and Administrative | | | | | | | | | | | | |
Research & Development Expenses | — | 200.4 | 212.2 | 249 | — | 211.1 | | | | | | |
| | | | | | | | | | | | |
| 19.8 | — | — | 0.3 | 51.8 | 0.5 | | | | | | |
Impairment of Long-Lived Assets | | | | | | | | | | | | |
| | | | | | | | | | | | |
| 559.4 | 213.6 | 186.9 | 163.2 | 470.4 | 275.9 | | | | | | |
| 93.6% | 37.6% | 33.6% | 28.8% | 87.2% | 43.3% | | | | | | |
Interest and Investment Income | 15.9 | 16.8 | 19.1 | 21.3 | 18.7 | 17.3 | | | | | | |
| | | | | | | | | | | | |
| — | — | — | — | — | — | | | | | | |
| | | | | | | | | | | | |
| 0 | -0.1 | 0.2 | -0.3 | 0 | 0.3 | | | | | | |
Interest Expense and Other, Net | | | | | | | | | | | | |
Interest Income and Other, Net | | | | | | | | | | | | |
Loss on Extinguishment of Debt | | | | | | | | | | | | |
| | | | | | | | | | | | |
Total Non-Operating Income | 16 | 16.7 | 19.3 | 21 | 18.7 | 17.5 | | | | | | |
Income Before Provision for Income Taxes | 575.3 | 230.3 | 206.2 | 184.2 | 489.2 | 293.4 | | | | | | |
Provision for Income Taxes | 58.8 | 45.6 | 46.1 | 44.9 | 36.8 | 66.7 | | | | | | |
Provision for Income Taxes | | | | | | | | | | | | |
| | | | | | | | | | | | |
| 516.5 | 184.7 | 160.1 | 139.3 | 452.4 | 226.7 | | | | | | |
Net Income Attributable to Common Shareholders | 516.5 | 184.7 | 160.1 | 139.3 | 452.4 | 226.7 | | | | | | |
| 0.7 | 0.7 | — | 0.5 | 0.4 | 0.8 | | | | | | |
| 0.7 | 0.7 | — | 0.5 | 0.4 | 0.8 | | | | | | |
Basic Weighted Average Shares Outstanding | 268.4 | 272.6 | 275.7 | 284.5 | 285.6 | 289.2 | | | | | | |
| 268.1 | 270.1 | 275 | 281.7 | 285.8 | 285.2 | | | | | | |
Diluted Weighted Average Shares Outstanding | 278.5 | 284.4 | 286.3 | 293.5 | 291.5 | 294 | | | | | | |
| 572.8 | 227 | 200.3 | 177.2 | 485.1 | 290.4 | | | | | | |
| 10.2% | 19.8% | 22.3% | 24.4% | 7.5% | 22.7% | | | | | | |